HPLC in Pharma

How HPLC can help you meet the specific challenges related to water for pharmaceutical use

Understanding the role of HPLC and different levels of water purity in drug manufacture, analysis and pharmaceutical quality assurance

Water is essential to the pharmaceutical industry, as both a raw material and a solvent in the processing, formulation and manufacture of pharmaceutical products. Our white paper HPLC in Pharma Analysis: Why water purity matters is an essential guide that will help you to meet the specific water-related challenges associated with HPLC and the different water types used in the manufacture, analysis and quality control of life-saving drugs.

What's inside?

• Water, HPLC and big pharma: which water should I use? Meeting the dual challenge of maintaining purity whilst keeping contaminants down.
• Excipient in the final formulation: The quality of water selected depends on the intended use of the drug. Find out the facts.
• Manufacture of APIs and medicinal products: What is the acceptable grade of water to use in the different stages of pharmaceutical manufacture?
• Cleaning and rinsing equipment, containers and closures: Use pharmaceutical cleaning validation guidelines for all pharma equipment and packaging.
• Use of pure water for HPLC in drug manufacture and QA. How trace levels of water impurities in HPLC can degrade the quality of a pharmaceutical analysis.
• Dissolution testing: a key role for HPLC in pharmaceutical analysis. Drug dissolution testing provides critical in vitro drug release information.